Our Research

Cell Biology

Efficiently intervening in cancer requires understanding how normal cells function and how cancer cells are different. For example, how cells replicate, divide and transmit genetic material from a parent cell to daughter cells is not only essential for human life


世界杯365bet下载MicroRNAs (miRNAs) are a conserved class of small non-coding RNAs that assemble with Argonaute proteins into miRNA-induced silencing complexes (miRISCs) to direct post-transcriptional silencing of their complementary mRNA targets. Silencing is accomplished through a combination of translational suppression and destabilization

Cancer Genes

Cancer is a genetic disease, in which cancer cells arise from mutations of genes in an otherwise normal cell. The mutations are usually caused by either environmental insults on DNA or spontaneous errors in cellular processes, such as gene expression,

Cancer Stem Cells

There is growing evidence that perhaps all cancers include a distinct small subpopulation called cancer stem cells (CSCs). Analogous to normal tissue stem cells, CSCs are believed to engender tumors through self-renewal and subsequent differentiation into multiple cell types that

The CRISPR-Cas System

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated (Cas) proteins underpin an RNA-guided adaptive immune system that protects bacteria and archaea from invading genetic elements such as plasmids and phages. In the system, fragments from foreign DNA are